Games › NFL

Arizona Cardinals vs Los Angeles Rams prediction

NFL · Sunday, October 18, 2026 · 4:05 PM ET · SoFi Stadium · Fox

Result

Final: Arizona Cardinals 18, Los Angeles Rams 16 (Arizona Cardinals won). Mel’s pick (Los Angeles Rams win 83% of the time) was wrong. On the total, Mel’s lean was wrong.

Mel’s pick

Los Angeles Rams win 83% of the time in Mel’s Playbook’s default simulation of this game, saved before it started.

Projected score

Arizona Cardinals 22, Los Angeles Rams 33. 13% of the simulations finished as one-score games.

Mel vs the betting line

Mel’s margin (Los Angeles Rams by about 11.8) is close to the line (Los Angeles Rams −12.5), so there’s no real lean against the spread.

The total is 51.5; Mel projects 54.9 points, a lean to the over.

Recent form

Arizona Cardinals (1-4) scored 21.6 and allowed 32.4 points a game over their last 5.

Los Angeles Rams (2-3) scored 23.8 and allowed 24 points a game over their last 5.

Based on this season’s stats, injuries, rest, travel, weather and the betting market. Updated Oct 18, 2:30 PM ET.

See the full simulation

Mel’s Playbook Pro shows the range of likely totals and margins, player props and every factor behind the pick, and lets you tune the model (home field, injuries, momentum and more) and re-run the game.

Open in Mel’s Playbook Try the free demo game

Every default-model prediction is saved before the game and graded against the final score on our public results page. Simulations are estimates, not guarantees, and this is not betting advice. 21+ where applicable; if gambling is a problem, call 1-800-GAMBLER.