Indianapolis Colts vs Minnesota Vikings prediction
NFL · Sunday, October 25, 2026 · 1:00 PM ET · U.S. Bank Stadium · CBS
Result
Final: Indianapolis Colts 10, Minnesota Vikings 16 (Minnesota Vikings won). Mel’s pick (Minnesota Vikings win 68% of the time) was right. On the total, Mel’s lean was right.
Mel’s pick
Minnesota Vikings win 68% of the time in Mel’s Playbook’s default simulation of this game, saved before it started.
- Indianapolis Colts: 32%
- Minnesota Vikings: 68%
Projected score
Indianapolis Colts 17, Minnesota Vikings 23. 18% of the simulations finished as one-score games.
Mel vs the betting line
Mel’s margin (Minnesota Vikings by about 6.4) is close to the line (Minnesota Vikings −6.5), so there’s no real lean against the spread.
The total is 41.5; Mel projects 39.5 points, a lean to the under.
Recent form
Indianapolis Colts (2-4) scored 24.2 and allowed 24.6 points a game over their last 5.
Minnesota Vikings (5-0) scored 21.8 and allowed 12.8 points a game over their last 5.
Based on this season’s stats, injuries, rest, travel and the betting market. Updated Oct 25, 11:28 AM ET.
See the full simulation
Mel’s Playbook Pro shows the range of likely totals and margins, player props and every factor behind the pick, and lets you tune the model (home field, injuries, momentum and more) and re-run the game.
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Every default-model prediction is saved before the game and graded against the final score on our public results page. Simulations are estimates, not guarantees, and this is not betting advice. 21+ where applicable; if gambling is a problem, call 1-800-GAMBLER.